Designing of Anti-Cancer Drug Targeted to Bcl-2 Associated Athanogene (BAG1) Protein
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A plant Bcl-2-associated athanogene is proteolytically activated to confer fungal resistance
The Bcl-2-associated athanogene (BAG) family is a multifunctional group of proteins involved in numerous cellular functions ranging from apoptosis to tumorigenesis. These proteins are evolutionarily conserved and encode a characteristic region known as the BAG domain. BAGs function as adapter proteins forming complexes with signaling molecules and molecular chaperones. In humans, a role for BAG...
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